Application of Flow Chemistry in API Synthesis
  • Day1
Friday, 11th February 2022

13:00

Welcome address and Introduction to the Tutor

13:05

Introduction to micro reactors and flow chemistry
Paul Watts, Research Chair in Microfluidic Bio/Chemical Processing, Nelson Mandela University, South Africa

A brief introduction to the type of reactors used will be given, but most time will be devoted to the key concepts such as heat transfer and mixing.

13:30

Reactions in flow chemistry
Paul Watts, Research Chair in Microfluidic Bio/Chemical Processing, Nelson Mandela University, South Africa

This section will review in detail the reactions related to the following with respect to API synthesis like Homogeneous liquid-phase reactions, Multi-phase reactions and catalysis, High temperature chemistry, Photochemistry, Electrochemistry

14.45

Break

15:00

Scaling-up in Flow
Paul Watts, Research Chair in Microfluidic Bio/Chemical Processing, Nelson Mandela University, South Africa

Application of technology for Industrial Scale Manufacture and Scale up

15:45

Case Studies
Paul Watts, Research Chair in Microfluidic Bio/Chemical Processing, Nelson Mandela University, South Africa

 Flow chemistry case studies with special reference to pharma industry

16:15

Challenges in flow chemistry
Paul Watts, Research Chair in Microfluidic Bio/Chemical Processing, Nelson Mandela University, South Africa

Challenges faced by scientists and chemists in implementing and scale up of flow chemistry in organic synthesis

16:45

Q/A Session

17:00

Closing Remarks and End of the Training Course

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