Genome editing can be simply defined as a suite of tools that enable us to modify the DNA in a more precise and accurate manner than ever before. The CRISPR/Cas9 method was hailed as a breakthrough invention by Science in 2015. The technology has been successfully validated and several updates have been added to the armory since then. Clinical trials with modified human DNA in somatic cells are already underway and several more are anticipated to follow. This is where the exciting merger of Precision Medicine and Human Genome editing takes place.
Precision Medicine as practiced today is confined to understand the implications of existing mutations together with their penetration in terms of Gene Expression and the effect of corresponding human microbiome. An integrated platform for practicing Precision Medicine is available.
The ability to add Genome editing aka Gene therapy to the current genre of Precision Medicine tools would be an exciting dawn of human healthcare assisted by supercomputers and quantum computers.