As environmental and safety regulations become more stringent, the pharma and chemical industries are increasingly looking to continuous flow manufacturing as an inherently safer, more efficient, and less costly alternative to traditional batch processing.
Indian API industry approached flow chemistry operations, when a market opportunity was detected. Since then, flow technology has been essential to develop processes that involve hazard reagents and high exothermic reactions to become inherently safer. The great R&D work performed now a days in API Generic Industry leads to a flow chemistry technology which is not only scalable but enables seamless scale-up. This talk focuses on several cases of flow processes to illustrate flow synthesis applied to pharmaceutical industry as well their transposition from lab scale to the production scale and their limitations.